Place |
Name |
Characteristic in the rating |
1 | Essentiale Forte N | Bestseller. double action |
2 | Phosphogliv | Anti-inflammatory activity. A complex approach |
3 | Essliver Forte | Enriched composition (6 vitamins). Quick Help |
4 | Rezalut Pro | Oxygen-free technology. Cholesterol-lowering effect |
1 | Hofitol | Best for toxemia in pregnancy. Minimum contraindications |
2 | Liv-52 | Popular phytopreparation. For adults and children from 6 years old |
3 | Karsil | The best support. Low percentage of adverse reactions |
4 | Holenzim | Combined hepatoprotector. The lowest price |
1 | Ursofalk | The best release form (suspension). For the little ones (0+) |
2 | Urdox | The best Russian analogue. Immunomodulatory action |
3 | Ursosan | Expensive medicine. Tablets and capsules |
1 | Heptral | High efficiency. Antidepressant activity |
2 | Heptor | The best for prevention. Normalization of digestion |
1 | Hepatrin | Detoxification. Sachets |
2 | Ovesol | Choleretic effect. Filter bags |
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By hepatoprotectors is meant a group of drugs intended primarily to stimulate the regenerative process of the structural cells of the liver parenchyma (hepatocytes).Another function assigned to this kind of medicine is to protect the liver from various negative effects, whether it be poisons and toxins, alcohol, "chemistry", smoked and fatty foods, etc.
Until now, there is no single recognized classification of hepatoprotective drugs in medicine. Most often, drugs are divided into groups according to:
- with origin (natural, synthetic);
- with chemical composition (phospholipids, amino acids, vitamins);
- With mode of action (choleretic, antioxidant, etc.).
We have compiled a rating of the best hepatoprotective agents for you to make it easier for you to make a choice. Please note that some of the drugs listed in the rating are not dispensed from pharmacies without a prescription.
The best hepatoprotectors based on essential phospholipids
The intake of hepatoprotectors of this group ensures the restoration of the hepatic cell membrane by the principle of incorporating essential phospholipids into it. The peculiarity of the drugs presented in the category is the minimized risk of side effects.
4 Rezalut Pro
Country: Germany
Average price: 454 rub.
Rating (2022): 4.6
The drug "Rezalyut Pro" based on the extract of soy phospholipids is considered, along with other nominees of the rating, an effective hepatoprotector for restoring liver cells and improving the outflow of bile. A feature of the product is a unique oxygen-free technology that allows you to save the active substance without the addition of dyes and other "chemistry": the output is "pure" phospholipids enclosed in a vacuum shell.Among the indications for taking the medicine are chronic hepatitis, cirrhosis, stetohepatosis and toxic liver damage.
The result of taking a hepatoprotector is to normalize lipid metabolism due to lower cholesterol levels. Users share their observations in their reviews that at the end of the course, many unpleasant sensations in the liver area were eliminated - food began to be better digested, heartburn and stagnation in the gastrointestinal tract disappeared, and pain ceased to bother. In addition, capsules have proven themselves well for preventive purposes, for example, during periods of exacerbations or holidays, when tables traditionally crackle from an abundance of junk food and alcohol.
3 Essliver Forte
Country: India
Average price: 304 rub.
Rating (2022): 4.6
An affordable analogue of more expensive drugs is the hepatoprotector Essliver Forte. The strong point of this remedy is a composition enriched with 6 vitamins (E, B1, B2, B3, B6, B12), led by essential phospholipids. The combined preparation (multivitamins + phospholipids) boasts hepatoprotective, hypolipidemic and hypoglycemic properties.
The drug in a short time restores liver function and increases its detoxification role in case of cell damage due to various reasons. Users in the reviews note that the remedy helps well with problems with the gastrointestinal tract, which instantly affect the general well-being, the condition of the skin, hair and nails. Capsules, despite the considerable size, are swallowed easily.When reading the instructions, attention should be paid to side effects, which, unlike most drugs, are practically absent (allergies and possible discomfort in the epigastrium).
2 Phosphogliv
Country: Russia
Average price: 444 rub.
Rating (2022): 4.7
In 2001 Phosphogliv was awarded the Discovery of the Year nomination at the All-Russian Pharmaceutical Competition Platinum Ounce. Since then, the remedy has been a regular in the top of the most effective hepatoprotectors based on essential phospholipids. Doctors recommend it as an antiviral, hepatoprotective and membrane stabilizing agent: gelatin capsules are indicated for adults and children over 12 years of age for prevention (poor environment, stress, poor nutrition), recovery (overeating, alcohol and drug intoxication) and treatment (hepatosis, hepatitis, steatosis) liver.
This is the only hepatoprotector, according to the state registry, containing glycyrrhizic acid. The reviews emphasize that this is a relatively inexpensive Russian-made hepatoprotector with anti-inflammatory activity. The regimen involves the use of 1-2 capsules three times a day during meals for an average of 3 months. Upon completion of the course, you can safely count on the restoration of liver cells, the normalization of protein and lipid metabolism, and the improvement of the elasticity of the organ.
1 Essentiale Forte N
Country: France
Average price: 558 rub.
Rating (2022): 4.8
"Essentiale Forte N" is one of the most popular hepatoprotective drugs.If you are familiar with symptoms such as fatigue, loss of appetite and heaviness in the right hypochondrium, you should take a closer look at this remedy. The medicine contributes to the restoration of liver cells, which in turn favorably affects the improvement of metabolism and the functioning of the whole organism. The peculiarity of the drug is a double action: the drug is involved both in the active regeneration of hepatocytes and in their protection by providing an antioxidant effect. More than 200 clinical studies have confirmed: "This is an effective and safe drug."
The hepatoprotector goes on sale in the form of gelatin capsules of 30, 90 and 100 pieces per pack. A drug is dispensed from a pharmacy without a prescription. During the day, take 2 capsules during breakfast, lunch and dinner. Thus, the daily dosage is 6 capsules, and this moment causes indignation among a number of users. Of the positive in the reviews, they mention a rapid improvement in the condition after poisoning, a pleasant smell of capsules, and a small percentage of side effects. Many pregnant women shared that the medicine helped them relieve the symptoms of toxicosis.
The best hepatoprotectors of plant and animal origin
The peculiarity of such hepatoprotectors lies in their ability to accelerate the recovery of liver cells during the treatment of cirrhosis, hepatitis, alcohol damage, liver failure and other organ pathologies.
4 Holenzim
Country: Belarus
Average price: 134 rub.
Rating (2022): 4.5
The winner in the nomination "Best Price" is the hepatoprotector of the Belarusian manufacturer "Holenzim".Experts recommend this combined animal remedy for the treatment of liver diseases and functional disorders of the gastrointestinal tract, as well as a powerful medicinal support.
The tool has a pronounced cholekinetic action, helps to improve the functional state of the gastrointestinal tract and normalize the process of assimilation of food. The reviews confirm that the hepatoprotector improves the functioning of the digestive system, eliminates stagnation of bile, bitterness and dryness in the mouth, relieves pain in the epigastric region. Swallowing tablets does not cause difficulties, allergic reactions are rare.
3 Karsil
Country: Bulgaria
Average price: 347 rub.
Rating (2022): 4.5
Means of plant origin "Karsil" is based on the extract of spotted milk thistle (silymarin). This component supports the liver, promotes cell regeneration, reliably protects against toxic substances and free radicals. Indications for treatment with a drug with a hepatoprotective and antioxidant effect are toxic lesions and chronic inflammatory liver diseases. However, the preventive orientation brought the greatest popularity to the hepatoprotector.
The drug goes on sale in the form of dragees, which is a big plus, judging by the reviews. Users emphasize that the pills are swallowed easily, without leaving an unpleasant aftertaste. The small percentage of side effects cannot but rejoice. For the most part, the remedy is prescribed as a maintenance measure during or after the completion of a course of antibiotics.Also, the medicine is considered a good sorbent, which comes to the rescue in case of poisoning and intestinal disorders. The price is not cheap, but acceptable.
2 Liv-52
Country: India
Average price: 298 rub.
Rating (2022): 4.6
Liv-52 has been produced in India since 1955. This is a combined herbal remedy that has antitoxic, hepatoprotective, cholekinetic and antioxidant action. The high efficiency of the phytopreparation in relation to liver pathologies is due to well-chosen components of the composition (prickly capers, chicory, black nightshade, etc.). The medicine helps to regenerate liver cells, enhance intracellular metabolism, prevent the formation of gallstones and improve its contractile function.
Hepatoprotector is in stable demand in pharmacies. The reviews are divided - "Do not expect a quick effect, because it's herbs!". At the end of the jar (on average, enough for 17 days of admission), there is a surge of strength, cholesterol returns to normal, digestion of food is no longer accompanied by discomfort. Slowly but surely, liver cells are restored.
1 Hofitol
Country: France
Average price: 344 rub.
Rating (2022): 4.7
Hepatoprotector "Hofitol" is characterized by a pronounced choleretic effect. The key to the effectiveness of the drug is a well-chosen complex of active substances. Carotene, riboflavin, thiamine, ascorbic acid and inulin, which are part of the leaves of the field artichoke, are responsible for the normalization of metabolic processes in the body.The tool is also famous for its extensive antioxidant and antitoxic effect, and thus favorably affects the protection and restoration of liver cells.
Tablets of plant origin "Hofitol" - one of the most commonly prescribed drugs for toxicosis. The instructions say that pregnancy and lactation are not a contraindication, however, taking this hepatoprotector is possible only under the supervision of a doctor. With a mild degree of toxicosis, the effect is felt almost instantly, with a stronger one - on the third or fourth day of admission. Such advantages of the drug as herbal origin, affordable cost and a minimum of contraindications overshadow the high consumption of tablets - 2-3 pcs. three times a day.
The best hepatoprotectors of synthetic origin
The most effective hepatoprotectors today are drugs for the treatment and prevention of liver pathologies of synthetic origin. Ursodeoxycholic acid, which is part of them, helps to activate the excretion of bile, lower cholesterol, and improve pancreatic and gastric secretion. Most importantly, there are no age restrictions for this active substance. Such medicines are safe even for the smallest.
3 Ursosan
Country: Czech
Average price: 872 rub.
Rating (2022): 4.7
The manufacturer offers hepatoprotector "Ursosan" in tablets and capsules. The latter are most in demand, as the reviews show. This drug is mainly used by adults and children over 3 years old. The medicine helps well in cleansing the liver of toxins and toxic substances, getting rid of bitterness in the mouth and relieving pain syndromes.In addition, it is an effective remedy for serious diseases, such as hepatitis of various origins, cholelithiasis, hepatosis, etc.
Users emphasize that the agent affects hepatocytes with a long course of treatment, as a rule, the result becomes replaced after 3 months of use. So don't expect instant results. Due to the duration of taking the drug and the consumption of capsules (2-3 capsules per day), the hepatoprotector significantly hits the pocket.
2 Urdox
Country: Russia
Average price: 772 rub.
Rating (2022): 4.8
The hepatoprotective agent "Urdoksa" is famous for its immunomodulatory, cholekinetic, cholelitholytic, hypolipidemic and hypocholesterolemic effect. The list of indications for treatment of the drug includes various pathologies of the liver and gallbladder (cirrhosis, stones, reflux gastritis, biliary dyskinesia, etc.). When reading the instructions, the duration of therapy is striking - from six months to a year.
In the reviews, the remedy is called a cheaper analogue of Ursosan, noting that this hepatoprotector is in no way inferior to the latter in efficiency. The first results make themselves felt somewhere after a month: pain in the hypochondrium disappears, dry mouth disappears, stool normalizes. Medium-sized capsules are not hard, so they are swallowed quite easily. Side effects are practically not observed.
1 Ursofalk
Country: Germany
Average price: 1 120 rub.
Rating (2022): 4.9
A feature of the hepatoprotector for the normalization of liver function "Ursofalk" is the release of the drug in the form of a suspension for oral administration.This form is preferred for children under 3 years of age based on ease of use. For older children and adults, the manufacturer also provides the drug in tablets and capsules. As for the suspension, users emphasize that it has a pleasant lemon taste, so babies rarely try to spit it out. The included measuring cup makes dosing easy.
Unanimously, the disadvantages, judging by the reviews, include a large volume. You can store an opened bottle for only 4 months, and the course of treatment does not require all 250 ml of the composition, and sometimes nothing at all is needed, for example, 50 ml. Thus, part of the funds remains unclaimed. But the advantages of the drug more than cover such a flaw as the lack of a small volume bottle, and the high cost. The medicine quickly normalizes blood counts, in particular, it helps with jaundice, quickly lowering bilirubin.
The best amino acid hepatoprotectors
Preparations from this category are recommended for those who have experienced severe liver damage. Please note that the main active ingredient of this kind of funds (ademetionine) provides for the likelihood of developing a large number of negative side reactions. For this reason, amino acid hapatoprotectors are rarely prescribed.
2 Heptor
Country: Russia
Average price: RUB 1,029
Rating (2022): 4.8
"Geptor", like other drugs from the category of amino acid hepatoprotectors, has antidepressant activity, choleretic and cholekinetic action. Indications for taking this medication are hepatitis of various origins, intrahepatic cholestasis, cirrhosis and a number of other pathologies associated with the work of the organ.This is an excellent medicine for removing harmful substances from liver cells, protecting and preventing liver dysfunction.
In the absence of symptoms of an "oppressed" liver, two tablets per day are sufficient. Thus, two packs of 20 pieces are enough for a 20-day prophylactic course of administration. For the treatment of specific liver pathologies, you will have to consult a doctor for the exact dosage and duration of the course, since this is a purely individual moment. As for side effects, the reviews note that during the first week, such troubles as nausea and diarrhea are often observed, apparently, these symptoms are accompanied by intensive cleansing of the liver. However, soon the discomfort is replaced by the first positive results - energy appears, mood rises, heaviness in the side goes away, appetite improves.
1 Heptral
Country: Italy
Average price: 1 590 rub.
Rating (2022): 4.9
Hepatoprotector "Heptral" is distinguished by antidepressant activity. Among the directions of the drug are also neuroprotective, choleretic, antioxidant and detoxifying effects. The tool is designed to fill the deficiency of ademetionine and activate its production. The drug increases the resistance of liver cells to negative factors, which in turn has a positive effect on the structure of the liver and its functioning.
“Expensive but effective!” - users write in the reviews. Indeed, the hepatoprotector is in the top of the most expensive. The course of treatment is usually about 3-4 weeks, during which 2-4 tablets should be taken daily twice or thrice a day.Thus, a pack of 20 pieces is enough for a very short period, and to complete the course, you have to buy more and more. The advisability of taking the drug can be judged by the results of repeated tests - they return to normal.
The best vitamin-like hepatoprotective agents
Dietary supplements as hepatoprotectors are not the most common occurrence. Such drugs, as a rule, do not guarantee the expected therapeutic effect. However, some drugs still managed to establish themselves as quite effective.
2 Ovesol
Country: Russia
Average price: 168 rub.
Rating (2022): 4.7
Carefully cleanse the liver of toxins promises the drug "Ovesol". In pharmacies, dietary supplements are presented in the form of tablets, solutions and filter bags. It is tea that is especially popular due to the choleretic herbs added to the branded composition. The manufacturer emphasizes that we have a 100% natural remedy: oats, volodushka, rosemary, rosehip, peppermint. Specially selected herbal ingredients have detoxifying, anti-inflammatory, analgesic and restorative properties.
Reviews confirm that the tool works. At the end of the course (20 days), you can notice an improvement in appetite and normalization of the digestive system as a whole, the absence of pain in the liver and bitterness in the mouth, getting rid of rashes on the face, etc. Among the advantages of this form of supplement release are low cost and unobtrusive herbal taste without bitterness. Tea in filter bags is recognized by users as an effective measure for the prevention and correction of minor disorders in the liver. It is recommended to repeat the course 3-4 times a year.
1 Hepatrin
Country: Russia
Average price: 519 rub.
Rating (2022): 4.8
"Hepatrin" is a unique complex of B vitamins and amino acids at an attractive price. L-ornithine, inositol and taurine, which are part of the detox drink, ensure the removal of toxins from hepatocytes, the natural restoration of liver functions and the protection of the organ from obesity. The drug does not contain GMOs, gluten and sugar. The dietary supplement has a hepatoprotective and detoxifying effect. The main advantages of the remedy are the dosage, frequency rate and duration of the course, namely, only 1 sachet per day after a meal for 10 days.
The reviews mention the pleasant taste of the drink and the quick relief from the feeling of heaviness after eating. A good bonus is the reduction of pimples and evening out the tone of the face. For those who, for some reason, are uncomfortable taking the remedy in the form of a detox drink, for example, the fact that the powder is very fine and dusty when poured into a glass, the manufacturer has an alternative - a remedy in capsules.