Place |
Name |
Characteristic in the rating |
1 | Suprastin | The most popular drug of the first generation |
2 | Tavegil | Ideal for skin manifestations of allergies |
3 | Diazolin | Valid for 48 hours |
4 | Diphenhydramine | Best price |
5 | Fenistil | Drops, gel and emulsion |
1 | Claritin | Suitable for motorists |
2 | Tsetrin | Acts gently but effectively |
3 | Kestin | Best action up to 72 hours |
4 | Loratadine | Minimum contraindications |
5 | Ketotifen | Effective allergy prevention |
1 | Zodak Express | Starts working within 10-15 minutes after taking |
2 | Erius | Eliminates itching, runny nose and watery eyes |
3 | Allegra | Best for seasonal rhinitis |
4 | Xizal | Better Relief of Advanced Allergy Symptoms |
5 | Desal | The most affordable modern drug |
Read also:
Almost every person experiences various manifestations of allergies from time to time. For some, this is a one-time reaction to an insect bite or an exotic product, while for others, sneezing, a runny nose, a rash, and other unpleasant symptoms are noted almost constantly.It is especially difficult for those who have an unpleasant reaction to allergens that are completely harmless to healthy people and occur almost every day - pollen, dust, cat hair, nuts, and the sun released during the flowering of trees. If adults in the majority are gradually getting used to life with allergies, then children have a much harder time.
On the shelves of pharmacies there is a rather large list of antihistamines, which are conventionally divided into three generations. Each of them has its own characteristics, advantages and disadvantages, but all are still used in medical practice. We have compiled a rating of the best allergy remedies of each generation, taking into account the popularity and effectiveness of drugs, reviews of doctors and ordinary people, the cost of the drug and the level of trust in its manufacturer.
Best First Generation Allergy Remedies
1st generation allergy remedies appeared in 1937, but remain relevant today. They have a pronounced sedative effect, often causing drowsiness, dizziness and decreased concentration. Many of the first-generation drugs only work for a few hours, so you will have to take them several times during the day. One of the advantages of a number of drugs from this group is the presence of an injection form, which is indispensable for acute allergy attacks, for example, Quincke's edema.
5 Fenistil
Country: Switzerland
Average price: 440 rub. (20 ml)
Rating (2022): 4.5
Fenistil is a drug at the junction of the first and second generation of antihistamines. It is available in the form of drops for oral administration, which are allowed for children from 1 month of age, as well as in the form of a gel and emulsion.The drug is most effective for getting rid of skin manifestations of allergies, and this applies to the release form for both external and internal use. After ingestion, the drug acts for a day, the gel can be applied 2-4 times a day.
It should be borne in mind that the drug has a slight sedative and hypnotic effects. It is not allowed to use during lactation and in the first trimester of pregnancy. Special care must be taken by people whose activities require increased concentration.
4 Diphenhydramine
Country: Russia
Average price: 33 rub. (10 ampoules 1 ml)
Rating (2022): 4.5
Founder of medicines for allergies. Simultaneously with the antihistamine property, it exhibits a hypnotic effect. In addition, Diphenhydramine is included in the well-known triad. The antihistamine action is quite fast, but short-lived. Effective against manifestations of reactions on the skin, rhinitis, Quincke's edema. It is used for allergies to pollen and the sun. Recently, the drug is used mainly in injectable form and more and more in a hospital setting. For self-administration at home, there are many more effective and safe means.
Approved for use by children after a year. During pregnancy and lactation is prohibited. Caution should be taken when accepting people whose activities require quick decisions. The tool is popular due to its affordable price.
3 Diazolin
Country: Russia
Average price: 42 rub. (10 tab. 50 mg)
Rating (2022): 4.7
Inexpensive, well-known to doctors and patients, the drug is available in tablets and dragees of 50 and 100 mg.It quickly relieves symptoms caused by allergies to pollen, medicines, insect bites, pet hair, especially cats, and serves as a prevention of rhinitis. A fairly popular remedy has a quick effect, after 15 minutes symptoms are relieved. This action can take up to 2 days.
Due to the effect on the nervous system, caution should be exercised. The elderly are not recommended, as well as pregnant and lactating women. Children can be taken from the age of 3, but strictly according to the doctor's prescription. The dose of the drug is selected individually, for adults it can be 50-200 mg 1-2 times a day.
2 Tavegil
Country: Russia
Average price: 230 rub. (20 tab. 1 mg)
Rating (2022): 4.8
Tavegil is a drug for allergies based on such an active substance as clemastine. It is often prescribed for skin allergic reactions to the sun, insect bites, and also helps with hay fever, including rhinoconjunctivitis. Relating to first-generation antihistamines, Tavegil is quite popular among patients. It costs almost 2 times more than its main competitor Suprastin, but it is enough to take it twice a day.
Doctors leave about Tavegil both positive and sometimes unflattering reviews. The main claims against him are associated with side effects in the form of drowsiness, lethargy and impaired coordination of movement. Many allergy sufferers take this remedy for many years and not everyone experiences unpleasant side effects.
1 Suprastin
Country: Hungary
Average price: 120 rub. (20 tab. 25 mg)
Rating (2022): 4.9
Works within 15-30 minutes. It is the leader in the ranking among first-generation antihistamines.A single dose eliminates the problem for 6 hours. The manufacturer produces the drug in the form of tablets and ampoules. But injections are prescribed in special cases when immediate assistance is required. And under the supervision of a doctor.
Reception for children after one month of life is possible, but this only applies to injections. Pregnancy and lactation are contraindications. In adults, the risk group includes the elderly and drivers. The first drug is prescribed very carefully, because they often experience side effects in the form of dizziness and drowsiness. Drivers are not recommended to use the drug, since Suprastin slows down the speed of psychomotor reactions and has a hypnotic effect. It is also forbidden to use it in acute bronchospasm.
Best Second Generation Allergy Remedies
Second-generation antihistamines do not cause drowsiness if the dosage is observed, however, in the case of individual sensitivity, some patients may still experience a slight sedation. The advantage of these drugs is the prolonged action and the ability to take once a day, as well as the availability of a release form in the form of drops approved for children. In some cases, these drugs can have a negative effect on the work of the heart, but this happens only in the presence of concomitant diseases.
5 Ketotifen
Country: Russia
Average price: 67 rub. (30 tab. 1 mg)
Rating (2022): 4.5
Ketotifen is the best choice for the gentle prevention of symptoms, the elimination of mild allergic reactions. The tool comes in tablets of 30 pieces, sealed in a plate. It contains the active ingredient ketotifen supplemented with cellulose, magnesium, silicon, sodium and lactose.The formula is indicated to relieve the symptoms of chronic urticaria, allergic rhinitis, conjunctivitis, dermatitis. It helps with reactions to cat fur, itching from blooms or pollen.
The formula does not remain in the body, most of the dose is excreted in 2 days. The shelf life of the drug is as much as three years, buyers are advised to keep it in a home first aid kit. Judging by the reviews, the remedy is recommended by doctors to those who do not need to "poison" the body with powerful substances. However, there is a minus, because of which Ketotifen took the last place in the group. It has a strong hypnotic effect, half an hour after taking the eyes themselves begin to close.
4 Loratadine
Country: Russia
Average price: 75 rub. (30 tab. 10 mg)
Rating (2022): 4.6
Loratadine is the best choice for the safe management of allergy symptoms. In Russia, it is included in the list of vital funds approved by the government. The drug is indicated to reduce the symptoms of seasonal allergies: to flowering, pollen, sun. It is in the form of a colorless solution with a yellow tint or tablets. The composition is supplemented with citric acid, sorbitol, there are flavoring additives. Loratadine reduces the risk of edema, spasms of blood vessels and bronchi, relieves itching after contact with cats and dogs.
Buyers note that the first changes appear in half an hour. They are noticeable on the skin, then the secretion of mucus decreases. The formula shows full strength after 8 hours, it is valid for a day. The substance is completely absorbed into the gastrointestinal tract and excreted from the body in 2 days. The tool is indicated for adults and children from 2 years old, but it contains alcohol in the composition.The formula is not addictive with prolonged use.
3 Kestin
Country: Spain
Average price: 420 rub. (10 tab. 10 mg)
Rating (2022): 4.7
Kestin is an antihistamine based on ebastine. It is available in the form of regular and lyophilized tablets, the latter are convenient to take anywhere, because. they are meant to be absorbed. The tool begins to act after 60 minutes. Efficiency lasts up to 48 hours, and after a 5-day intake, another 3 days are valid. It is used for angioedema, conjunctivitis, rhinitis caused by flowering, hay fever (reaction to pollen).
Due to side effects in the form of lethargy, drowsiness, decreased performance, and effects on the heart, the drug is contraindicated in children under 12 years of age. From 12 to 15 years old, take no more than 10 mg per day. Whereas for adults and adolescents after 15 years of age, the allowable dosage is 2 times higher and is 20 mg. The drug is prohibited for pregnant and lactating women. Not recommended for drivers, as Kestin helps to reduce concentration.
2 Tsetrin
Country: India
Average price: 220 rub. (30 tab. 10 mg)
Rating (2022): 4.8
Cetrin rightfully occupies a high position in the ranking of the best allergy remedies. The medicine begins to exert its effect within 30 minutes after ingestion, and the effectiveness lasts up to a day. Fights various manifestations of an allergic reaction caused by cats, dust, blooms and other irritants. Eliminates not only the symptoms, but also the very cause of allergies. Helps to cope with itching, sneezing, lacrimation, redness of the skin.
Previously, Cetrin was also offered in the form of syrup and drops for oral administration, but for 2021 only a tablet form is available. This did not make the drug less popular, and the reviews about it still sound only positive. The medicine acts gently, rarely causes side effects, but works great, relieving allergies for up to 24 hours.
1 Claritin
Country: Belgium
Average price: 380 rub. (30 tab. 10 mg)
Rating (2022): 4.9
The leader of the ranking among second-generation allergy remedies. The action begins after half an hour, and the effect lasts up to a day. It copes well with hay fever (pollen allergy) and various skin reactions caused by the hair of cats and other pets, food, insect bites. Claritin has almost no side effects and contraindications. Reviews say that drowsiness does not occur when taking, concentration of attention does not decrease. Drivers can take this drug without fear.
Claritin is able to influence the functioning of the heart muscle, some people still experience drowsiness while taking it, so it is better to take the pill in the evening, and not in the morning. Recommended for children from 2 years old. Nursing mothers and pregnant women should refrain from taking it.
Best Third Generation Allergy Remedies
Third generation allergy medicines are the most modern, safe and effective. They contain active metabolites that minimize the risk of negative effects on the heart and liver. After taking these drugs, drowsiness does not occur, so they are allowed even when driving.One tablet a day is enough to forget about allergies and live a free life.
5 Desal
Country: Malta
Average price: 235 rub. (10 tab. 5 mg)
Rating (2022): 4.4
Desal is a relatively inexpensive, but very high-quality generic based on desloratadine. It begins to act literally within 30 minutes after ingestion and remains active for a day, which will allow you to drink tablets only 1 time per day. The medicine is prescribed to eliminate all manifestations of rhinitis after contact with pollen, cat hair, dust and other allergens, as well as to relieve skin itching, including that resulting from a reaction to the sun. Children are allowed only from the age of 12.
The annotation to the drug contains a very significant list of side effects, but they are practically not mentioned in the reviews, which allows us to talk about the high safety of the drug. Desal costs much more affordable than the original drug desloratadine.
4 Xizal
Country: Switzerland
Average price: 682 rub. (14 tab. 5 mg)
Rating (2022): 4.5
The Swiss drug Xyzal is a powerful antihistamine. The active substance levocetirizine blocks receptors, affects the development of allergies. It quickly removes markers of inflammation, reduces vascular permeability. The drug has proven effectiveness in itching, swelling, redness. It is prescribed for seasonal allergies to pollen and flowers, or to soothe the skin after the sun. The formula practically does not interact with other drugs.
Sealed Xyzal is stored for up to 3 years, although it must be used within 3 months when opened.The tool comes in the form of drops and tablets, the action lasts 2 days. The substance is then excreted from the body. It is indicated for adults, it is not recommended for children. Judging by the reviews, the drug is used to treat allergic rhinitis and dermatitis on the skin. There are comments from patients who take the medicine for several months. They talk about lack of addiction.
3 Allegra
Country: France
Average price: 610 rub. (10 tab. 120 mg)
Rating (2022): 4.5
The antihistamine drug Allegra is a fexafenadine-based tablet manufactured by the French company SANOFI. Two dosages are available in pharmacies - 120 and 180 mg, the first is indicated for allergic rhinitis, and the second for chronic urticaria. The drug quickly blocks the symptoms, relief occurs an hour after ingestion, and the effect lasts up to a day.
It has many side effects compared to similar drugs. It affects the functioning of the heart and kidneys. Therefore, the elderly are prescribed with caution. Children are allowed to take from 12 years. In addition, Allegra can dull concentration, so it is rarely prescribed to drivers. Pregnant women, due to insufficient data on the effect on the fetus, the drug is not recommended. Prohibited for admission during lactation.
2 Erius
Country: Belgium
Average price: 680 rub. (10 tab. 5 mg)
Rating (2022): 4.8
Erius - tablets and syrup based on desloratadine. The drug is used against allergies caused by pollen, flowering, cat hair and other irritants. Eliminates symptoms such as itching, sneezing, watery eyes, cough, runny nose. It is possible to take children from the age of one (for syrup).Medicine in the form of tablets is permissible to use from 12 years.
Quite expensive Erius receives a lot of positive feedback from doctors and patients. It can cause side effects, but they appear no more often than when taking other allergy medications. Many doctors call it one of the best, others say that it is not effective enough in some cases.
1 Zodak Express
Country: Czech
Average price: 550 rub. (28 tab. 5 mg)
Rating (2022): 4.9
Zodak Express is a modern antihistamine drug, the action of which begins literally 10-12 minutes after administration. Produced on the basis of levocetirizine, it is available in tablet form, approved for use by both adults and children over 6 years of age. Indications for use are allergic rhinitis and conjunctivitis, hay fever, skin rashes, accompanied by itching. One tablet a day is enough to relieve all symptoms.
Doctors and ordinary people highly appreciate the effectiveness of Zodak Express, leave positive feedback, confirming the quick action and the almost complete absence of side effects. The tool is not addictive, small tablets are convenient to take. The price seems too high to many, but this opinion can be classified as subjective.