Place |
Name |
Characteristic in the rating |
1 | Novartis Co-Exforge | complex composition. The highest price corresponds to the quality |
2 | Akrikhin Kapoten | The best rate of decrease in blood pressure during a sharp jump is in 5 minutes |
3 | Servier Prestarium A | Soft impact. Does not cause arrhythmia. Successful Clinical Trials |
4 | Zentiva Lozap Plus | The most convenient regimen for taking without being tied to food |
5 | Egis Dopegit | Popular tool. Suitable for pregnant women, the elderly and children over 3 years of age |
6 | Krka Lorista | cumulative effect. A minimum of "sides". Comfortable tablet form |
7 | Ozone Losartan | The best prolonged effect at a reasonable price. domestic manufacturer |
8 | Merck/Nanolek Concor | Directed action on the heart. Possibility of long-term treatment |
9 | Takeda Edarbi Klo | The best combination of two active ingredients for the treatment of advanced hypertension |
10 | Ozone Valsartan | Selective antagonistic action |
In the world, almost every 3rd adult, without even noticing it, experiences high blood pressure. The disease has greatly improved. If earlier it was recommended to control your body with a tonometer only for the elderly, today you should be wary from the age of 35. In the presence of such factors as overweight, poor nutrition, harmful working conditions, insufficient rest and constant stress, and even earlier.
Symptoms of the first degree of hypertension (140-159 / 90-99) can be completely invisible, but even such figures should not be taken lightly. Otherwise, the disease develops to the second (from 160 to 179/90–99) and third degree (above 180/110), which are fraught with a hypertensive crisis and irreversible damage to target organs. Different drugs have been developed for each condition. Our rating shows which pills are most effective, but although many are sold by prescription, a visit to the doctor is indispensable. It may be necessary to change several drugs in order for the treatment to pass without side effects.
TOP 10 best pills for high blood pressure
10 Ozone Valsartan
Country: Russia
Average price: 299 rub. (160mg #30)
Rating (2022): 4.1
When the task is to specifically influence the cause of high blood pressure, bypassing other systems, it is advisable to use tablets such as Valsartan. They act on AT1 angiotensin receptors, thereby providing selective opposition to the increase in pressure. The process does not block ion channels and receptors for other hormones that should support the function of the cardiovascular system. The level of uric acid, glucose and cholesterol in the blood plasma during the reception does not change.
The tool in the reviews is always highly rated. Even if the diagnosis was made decades ago, a 20-day course of administration normalizes the jumps to acceptable values. In the first week, there may be a headache and hypertensive jumps up to 150/90, then everything stabilizes. It is important to note that in 2018, the drug was recalled in a number of European countries due to the discovery of a probable carcinogenic component of NDMA in it.As it turned out later, a dangerous impurity got into the tablets from the raw substance. The manufacturer "Ozon" reacted by temporarily stopping the release of Valtarsan on the market and looking for a new supplier of raw materials. Judging by the fact that the pills reappeared on sale, he managed to establish the production of an effective and safe drug.
9 Takeda Edarbi Klo
Country: Japan (made in USA)
Average price: 804 rub. (40mg+12.5mg #28)
Rating (2022): 4.2
The formula with azilsartan (AT-1 antagonist) is fortified with the diuretic chlorthalidone. "Edarbi Klo" is prescribed for the treatment of high blood pressure, often in combination, if monotherapy does not cope with the task. The most pronounced effect of pressure reduction is observed towards the end of the monthly course, but relief occurs already on the 7-14th day after the start of administration. Elderly people under 75 do not need to worry about dose adjustments: the drug is tolerated normally without an increased risk of adverse events.
There is a risk group that requires a cautious approach and dose adjustment due to the potential development of hypotension - these are patients with a reduced volume of fluid or salts. One in a hundred may experience hypomagnesaemia, urticaria, loss of appetite, minor GI upset, impotence. In general, the drug effectively solves the problem of high blood pressure, but has a wide list of contraindications and incompatibility with other drugs.
8 Merck/Nanolek Concor
Country: Germany (produced in Russia)
Average price: 312 rub. (5 mg #50)
Rating (2022): 4.3
Merck is the world's oldest pharmaceutical and biochemical company based in Germany.Now the secondary packaging and initial quality control of the Concor drug is carried out at the Russian facilities of Nanolek. The remedy for high blood pressure with bisoprolol selectively blocks certain receptors, after which the frequency and strength of heart contractions decrease, and the conduction of the heart decreases. As a result, after the drug there is a decrease in pressure. The regimen of administration and dosage is selected by the doctor individually, after a careful study of the history and current state of health of the patient. Treatment can be prescribed for a long time, with chronic heart failure requires regular medical supervision.
The European drug is popular with our compatriots, there are quite a lot of reviews on the net. Of the advantages, the ability to quickly reduce the pulse, calm the arrhythmia, and restrain the pressure rushing upwards is distinguished. Cons - therapy is not always without side effects: nausea, vomiting, diarrhea, constipation, asthenia.
7 Ozone Losartan
Country: Russia
Average price: 130 rub. (50 mg #30)
Rating (2022): 4.5
Increased blood pressure can occur due to narrowing of the lumen of the blood vessels. This reaction is called vasoconstriction and occurs under the influence of angiotensin II. The rapid pathological process can be stopped with the well-known drug Losartan from the group of antagonists of the receptors of this hormone. Thus, this is the most promising long-acting drug (more than 24 hours). Long-term use causes a stable therapeutic effect, in most cases without side effects.
Tablets with losartan potassium from a Russian manufacturer are in good standing with hypertensive patients, since they are cheaper than imported analogues.It is convenient to take 50 mg of the active substance once a day; on the recommendation of a doctor, the dosage can be doubled or halved. A prescription is required to purchase, it is prescribed to patients over 18 years of age.
6 Krka Lorista
Country: Slovenia (produced in Russia)
Average price: 439 rub. (50 mg #90)
Rating (2022): 4.6
Film-coated tablets may contain different amounts of the active substance (losartan potassium), from 12.5 to 100 mg in 1 piece. Their oval shape and miniature size facilitate trouble-free swallowing. The drug is very effective when taken orally, has a hypotensive pharmacological effect and leads to a decrease in systolic and diastolic blood pressure. The prescription drug is prescribed for arterial hypertension, to protect the kidneys in patients with type 2 diabetes with proteinuria, against the background of chronic heart failure.
The medicine belongs to a new generation. Many clinical trials were conducted with it, and it was not without side effects: 1 out of 10 people tested experienced one of such phenomena as dizziness, anemia, vertigo, fatigue. But judging by the comments of consumers, the effect on the body is gentle, negative symptoms are rare, the main thing is to choose the right dosage.
5 Egis Dopegit
Country: Hungary
Average price: 231 rub. (250 mg #50)
Rating (2022): 4.7
Methyldopa as part of Dopegyt has a central effect on brain receptors.Its regular intake leads to a decrease in pressure through a number of mechanisms: a decrease in sympathetic tone, dopamine replacement, suppression of the synthesis of norepinephrine and a number of other hormones, as well as a decrease in plasma renin activity. This type of drug does not belong to the main antihypertensive formulas and is often prescribed in combination. The drug has been successfully used in pediatric practice since the age of three, and is also suitable for the treatment of elderly patients, subject to a gradual increase in dose.
Pregnant women drink pills on the advice of a doctor when a hypertensive crisis threatens the healthy bearing of a child. In the comments they write that the drug is quite safe, but with a slow and short-term effect. The active substance can disrupt concentration, therefore it is contraindicated for drivers and operators of mechanisms.
4 Zentiva Lozap Plus
Country: Czech Republic
Average price: 948 rub. (50mg + 12.5mg #90)
Rating (2022): 4.7
The drug has a triple effect - hypotensive, vasodilating, diuretic. The first helps to reduce high blood pressure. Vasodilation is the relaxation of smooth muscles in the walls of blood vessels. And the third component, a diuretic, is needed to reduce the volume of circulating blood and change the reactivity of the vascular wall. Such a powerful complex normalizes high blood pressure even in difficult cases, at the same time preventing the risk of serious cardiovascular problems, and also relieves swelling due to the diuretic component.
After taking the drug, patients feel relief, including in bad weather, but sometimes complain about the high price. Naturally, the best savings are seen when buying the largest pack of 90 tablets.It is convenient that the reception does not need to be adjusted to nutrition and calculate the optimal time. In addition to the main effect in the form of a decrease and absence of jumps in blood pressure, the drug provides a diuretic effect and relieves swelling.
3 Servier Prestarium A
Country: France (produced in Russia)
Average price: 491 rub. (5mg #30)
Rating (2022): 4.8
The drug "Prestarium" requires constant intake, but an effective decrease in pressure is observed quickly and with any degree of hypertension: mild, moderate and severe. Rapid absorption leads to the achievement of the maximum concentration in the blood in just 1 hour. Systolic and diastolic blood pressure falls regardless of the position of the body - standing or lying down. The active substance reduces the resistance of peripheral vessels, which contributes to increased blood flow without negative consequences for the heart rate.
Clinical studies have shown good results. The risk of fatal or disabling stroke decreased by 33%, non-fatal myocardial infarction - by 26%, post-stroke dementia - by 45%. The reviews praise the drug for effective prevention of stroke and real help with problems with the heart and blood vessels, but they blame it on an uncomfortable jar. It opens easily, but the tablets are shaken out with difficulty.
2 Akrikhin Kapoten
Country: Australia (produced in Russia)
Average price: 308 rub. (25mg #56)
Rating (2022): 4.9
A sudden attack of hypertension requires the most prompt response.To alleviate the condition, you need to put the tablet under the tongue and slowly dissolve - even before the end of the procedure, after 5-10 minutes, the result will appear. Its action is based on the properties of a substance called captopril. It is an ACE inhibitor and inhibits the formation of angiotensin II, while reducing pre- and afterload on the heart.
The taste is unpleasant, bitter, but for the sake of the result you have to endure, consumers write online. The medicine helps out with very high blood pressure, but is not intended to constantly keep the indicators normal. This is more of an ambulance than a systemic solution to the issue. If you do not adjust the dose, you can not do without side effects in old age. However, if the values jump above 140/90, and hypertension causes severe discomfort, such a pill must be carried by a hypertensive patient.
1 Novartis Co-Exforge
Country: Switzerland
Average price: RUB 2,548 (10mg+160mg+12.5mg #28)
Rating (2022): 5.0
Amlodipine is added to the formula - a calcium channel blocker (CCB), complex proteins through which calcium, sodium, barium and hydrogen ions pass. Second-generation CCBs have a better duration of action and higher tissue permeability. Properly selected treatment almost always passes without side effects. In elderly patients, even after 65 years, dose adjustment is not required.
Users say that this is a specific product. It causes a strong decrease in upper pressure, has a minimal effect on the lower and does not affect the pulse in any way.The high cost is dictated by the powerful composition (amlodipine + valsartan + hydrochlorothiazide), as well as the credibility of the manufacturer - the transnational pharmaceutical corporation Novartis. Hypertension drug Exforge is one of the best-selling in the world, it inspires confidence and brings its creators $926 million per year (data for 2016)