Place |
Name |
Characteristic in the rating |
1 | Micardis | The best drug based on telmisartan |
2 | Lorista | The most popular |
3 | Valsacor | Most effective in the treatment of acute myocardial infarction |
4 | Atakand | The original drug based on candesartan |
5 | Aprovel | The safest |
6 | Diovan | The original drug based on valsartan |
7 | Telmisartan | The latest generation of pressure relief |
8 | Losartan | Best price |
9 | Hyposart | Gentle pressure drop without sudden surges |
10 | Valsartan | The best combination of price and efficiency |
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In recent years, hypertension has been diagnosed in ever younger people, although more recently it was predominantly the elderly who suffered from it. It not only reduces the quality of life, but can also pose a serious threat to it. Complications against the background of high blood pressure are no less terrible, often leading to disability. Only regular visits to the doctor and the use of special drugs will help to avoid this, among which the most prescribed, as well as effective and safe, are angiotensin-2 receptor blockers (ARBs) or sartans.
We have prepared a rating of the best sartans, including preparations of both the first and the latest generation. When compiling the TOP, reviews of doctors and patients, compositions of medicines and their popularity were taken into account.
Comparison of the main characteristics of sartans and ACE inhibitors
In addition to sartans, ACE inhibitors (angiotensin-converting enzyme) are also used to treat hypertension. The latter are often also called pril because of the common ending in the name of the drugs - Enalapril, Captopril, Lisinopril. They have a slightly different mechanism of action, have recently been prescribed less frequently, and are considered less modern. ACE inhibitors block the conversion of angiotensin I to angiotensin II. Sartans act as angiotensin II receptor blockers, normalizing increased vascular tone.
Table comparing characteristics of sartans and ACE inhibitors (by-catch)
| Sartans | ACE inhibitors |
Impact on AII | The negative effect of AII is blocked completely | AII synthesis is reduced, but not completely stopped |
Influence on the bradykinin-kallikreinkinin system | Missing | There is a violation of degradation bradykinin |
Price | high | Low |
Side effects | Rare, comparable to placebo | Quite often, up to 5-7% |
Number of indications for use | Few | A lot of |
"Escape" neurohormonal actions | Weakly expressed | Significantly pronounced |
TOP 10 best and safest sartans
10 Valsartan
Country: Russia
Average price: 263 rub. (30 tab. 80 mg)
Rating (2022): 4.4
Valsartan is a very popular Russian generic of the Swiss drug Diovan. It has a rather attractive price, contains the active ingredient of the same name. The drug is prescribed for arterial hypertension and chronic heart failure, is available in a dosage of 80 or 160 mg. 1-2 doses are recommended per day, the maximum daily dose is up to 320 mg, a doctor will help determine it.The effect of the drug develops within two hours, the maximum effect occurs after 3-4 hours.
Valsartan is produced in Russia by several manufacturers, so the price may vary. Since the drug is a generic, many consider it not effective enough, but the reviews of patients who took the drug sound mostly positive.
9 Hyposart
Country: Poland
Average price: 355 rub. (28 tab. 16 mg)
Rating (2022): 4.4
Hyposart tablets contain candesartan cilexetil as an active ingredient, which is an angiotensin II receptor antagonist. They are available in dosages from 8 to 32 mg, the doctor will help you choose the right one. Just 1 dose per day will allow you to control blood pressure and will be the optimal maintenance therapy for heart failure.
The drug has a cumulative effect, so the maximum effect of its use can be seen in about 1 month. There are many side effects described in the annotation, but they occur extremely rarely. One of the advantages of Hyposart, in addition to a long action for 24 hours, is its mild effect and the absence of the effect of a sharp decrease in pressure.
8 Losartan
Country: Russia
Average price: 124 rub. (30 tab. 50 mg)
Rating (2022): 4.4
Losartan is a drug based on the active ingredient of the same name. It acts simultaneously gently and confidently, has a cumulative effect, has no withdrawal syndrome. The tool is equally effective in the use of both young and elderly people, helps to minimize the risks of heart attacks and strokes. Side effects are extremely rare and occur in a minimal number of patients, sartan is considered quite safe.
Tablets are available in dosages from 12.5 to 100 mg, offered by different manufacturers. Only a doctor can determine the correct dose of the drug. In most cases, one dose per day is sufficient. Losartan patients with arterial hypertension are prescribed for continuous use, which can significantly improve the quality of life, as evidenced by numerous reviews. Based on this active ingredient, other drugs are also produced (Lozap, Lorista), but they are more expensive.
7 Telmisartan
Country: Russia
Average price: 242 rub. (28 tab. 80 mg)
Rating (2022): 4.5
Telmisartan is an angiotensin II receptor antagonist based on the active substance of the same name. It is one of the latest generation of sartans, characterized by high safety and efficiency. One dose per day is enough to maintain normal pressure and prevent heart failure. The drug is approved for use in elderly patients, including those with liver failure.
Tablets are available in dosages of 40 and 80 mg. There is also an option with the addition of hydrochlorothiazide or amlodipine, which expands the effect of the drug. Based on telmisartan, several drugs are produced that differ in cost, but not in effect. What to choose - the doctor will tell you.
6 Diovan
Country: Switzerland
Average price: 1753 rub. (28 tab. 80 mg)
Rating (2022): 4.5
Diovan is an original drug with the active ingredient valsartan. Manufactured in Switzerland by Novartis Pharma. Tablets at a dosage of 80 and 160 mg are enough to take once a day.The drug has a cumulative effect, so you can fully feel its effectiveness after about 2-4 weeks of regular use. Dose adjustments are usually made during this period if necessary.
Diovan is produced in the so-called calendar packaging. This means that the day of the week is indicated on the blisters, which allows you not to miss a dose and not take an extra pill. There are few reviews about the drug, which is due to its high price and the presence of a large number of much more affordable and popular generics, the effectiveness of which is no worse.
5 Aprovel
Country: France
Average price: 630 rub. (28 tab. 150 mg)
Rating (2022): 4.5
The drug for hypertension Aprovel is made on the basis of such an active substance as irbesartan. It is available in dosages of 150 or 300 mg in packs of 14 or 28 tablets. One dose per day is usually enough to keep blood pressure within normal limits. The drug is recommended for continuous use, effective both in monotherapy and in combination with other drugs. The decrease in pressure against its background occurs slowly without the occurrence of hypotension, which makes it possible to classify it among the safest.
The main disadvantage of Aprovel for many patients is the cost of a monthly course. Otherwise, there are no complaints about the drug and reviews about it sound only positive. The summary of this medicine is quite extensive and detailed, so you should not prescribe it yourself. Let the doctor do it.
4 Atakand
Country: Sweden
Average price: 2736 rub. (28 tab. 16 mg)
Rating (2022): 4.5
Atacand is the most expensive drug based on such an active ingredient as candesartan. It is original, carefully researched and proven to be effective. Tablets are available in dosages of 8, 16 and 32 mg, which allows you to choose the optimal amount of active ingredient for each patient. Convenient reception once a day, prolonged action, which, with constant use, lasts up to 2-3 days, the absence of the effect of a sharp decrease in pressure - these are the main advantages of this remedy.
Atacand is considered one of the best drugs in its group, but the extremely high price does not allow it to be popular enough, especially given the large number of generics with much more attractive prices. There are few reviews about pills, but among them there are no completely negative ones.
3 Valsacor
Country: Slovenia
Average price: 376 rub. (30 tab. 80 mg)
Rating (2022): 4.6
Valsacor is the most popular drug based on valsartan. He is trusted by doctors and patients, recommended by pharmacists. The medicine is produced by the well-known company Krka in three dosage options - 80, 160 and 320 mg. Also, the drug is offered in combination with an additional active ingredient hydrochlorothiazide, which is a mild diuretic and is indicated if edema occurs against the background of increased pressure.
One tablet a day is enough to forget about arterial hypertension and return to normal life. There are many positive reviews about Valsakor. Most of those to whom it is indicated take the drug on an ongoing basis. The cost of a monthly course can be called quite affordable, especially in the case of purchasing a large package.
2 Lorista
Country: Slovenia
Average price: 215 rub. (30 tab. 50 mg)
Rating (2022): 4.6
Lorista is one of the most popular drugs for hypertension. It is most often prescribed to patients with high blood pressure, because the remedy combines high efficiency, reasonable cost and convenience of taking only 1 time per day. Tablets are presented in dosages of 12.5, 25, 50 and 100 mg, there is also an option with the addition of hydrochlorothiazide, which is a mild diuretic.
Most patients tolerate the drug well, without experiencing potential side effects. The cost of the drug is quite adequate. It is even more attractive when buying a package of 60 or 90 tablets. Positive feedback about Lorista is heard from both doctors and patients. Many take this drug for years, not planning to change it to another and being completely satisfied with the result.
1 Micardis
Country: Germany
Average price: 1150 rub. (28 tab. 80 mg)
Rating (2022): 4.7
Micardis is the latest generation of pressure medicine based on telmisartan. It is an original drug, therefore it is offered at a price much higher than generics with the same active ingredient. A single dose per day helps to effectively control blood pressure in both young and elderly people, few people face side effects of the remedy.
Tablets with a dosage of 40 or 80 mg are placed in convenient blisters with the indication of the day of the week, which allows you not to forget about taking the medicine. Reviews about Mikardis sound mostly good, but its cost is far from accessible to everyone.Thanks to active advertising, the patronage of doctors, as well as excellent efficiency, this sartan is used by many patients.