Place |
Name |
Characteristic in the rating |
1 | Ixel | The best remedy for depression with apathy and melancholy |
2 | Paxil | Quick result |
3 | Fevarin | Excellent performance and tolerance |
4 | Mirtazapine | The best combination of price and quality |
5 | Zoloft | High efficiency |
6 | Escitalopram | Powerful Action |
7 | Afobazole | The most popular and affordable drug |
8 | Trittico | Minimal side effects, no addiction |
9 | fluoxetine | Best price |
10 | Anafranil | Helps with severe, prolonged depression |
The modern rhythm of life requires maximum return from a person, gradually taking away his health, first of all, mental. Constant stress at school, work or at home, as well as financial and social problems affect the fragile nervous system. Many do not pay attention to the first signs of depression: poor appetite, apathy and irritability, and yet they are signals that cannot be ignored. To solve such problems, “light” new-generation drugs that have a sedative effect come to the rescue.
Types of antidepressants
Antidepressants are a large group of drugs that vary greatly in their action. They can be with a sedative and stimulating effect, depending on the mechanism of action. Basically, there are three major groups.
Tricyclic antidepressants appeared first. They are quite effective, but often give unwanted side effects. Most often it is weakness, dry mouth, daytime sleepiness, dizziness, decreased potency. Despite this, for many doctors they are the drugs of choice at the beginning of treatment, as they are well studied and give a predictable result.
MAO inhibitors have a stimulating effect. Their help is resorted to with minor depressions and in the event that treatment with tricyclic drugs has not given the expected result. But funds from this group are prescribed with caution, since they are not combined with many drugs.
Serotonin reuptake inhibitors - the newest class of antidepressants, which has the fewest side effects and contraindications. It includes many commonly prescribed drugs - Fluoxetine, Zoloft, Prozac, Paxil.
In addition to these three groups, there are antidepressants that have a different chemical composition and mechanism of action. As a rule, these are separate drugs, so they cannot be distinguished into a category.
The effect of treatment in any case appears no earlier than a week later. Most drugs require a long course followed by gradual withdrawal. In no case should you prescribe them to yourself, an incorrectly selected drug gives the risk of the opposite effect - increased depression or excessive arousal, up to the appearance of suicidal thoughts.Therefore, if it is not possible to consult a doctor, you can use only light over-the-counter remedies.
Top 10 Best Antidepressants
10 Anafranil
Country: Switzerland (made in Italy)
Average price: 307 rub.
Rating (2022): 4.6
Inexpensive tricyclic antidepressant used for depression of various etiologies and severity. It equally effectively relieves depressed mood, increased anxiety, and eliminates obsessive-compulsive states. It can only be used strictly according to the doctor's prescription, as it often gives undesirable side effects that require dose adjustment. It is not prescribed very often, mainly for severe, prolonged depression, when other drugs have not been effective enough.
Reception always begins with a small dosage, gradually increasing it until a stable therapeutic effect occurs. Cancellation of the drug should also be gradual. Along with effectiveness, side effects often occur in the form of dry mouth, urination disorders, drowsiness, decreased concentration and libido. Compared to other similar drugs, it has an affordable cost.
9 fluoxetine
Country: Russia
Average price: 96 rub.
Rating (2022): 4.7
One of the most common and affordable antidepressants from the group of selective serotonin reuptake agents. It has a pronounced stimulating effect, therefore it is often prescribed to patients with apathy, lethargy. In depression with anxiety, it can increase anxiety, which is eliminated by the simultaneous appointment of tranquilizers.It starts to act quite quickly, but not immediately - a tangible therapeutic effect is achieved after two to three weeks from the start of administration.
The antidepressant is usually well tolerated by patients, but it still gives a number of side effects. Most often they are manifested by a decrease in appetite, libido, nausea at the beginning of the course. Throughout the treatment, patients often complain of obsessive yawning. The advantages of the remedy include taking it once a day and a very low cost compared to analogues. The drug is good, but requires mandatory medical supervision at the beginning of the reception.
8 Trittico
Country: Italy
Average price: 832 rub.
Rating (2022): 4.7
A broad-spectrum drug actively used by psychotherapists to treat depression accompanied by anxiety and sleep disorders. Judging by the doctors' reviews, the medicine is already effective in small doses, it does not adversely affect the cardiovascular system, therefore it is also prescribed for the elderly. Unlike most of these drugs, it does not cause a decrease in libido, on the contrary, it can be used to correct erectile dysfunction against the background of depression.
The effect of taking the drug develops quite quickly, but at the beginning of treatment it is often overshadowed by daytime sleepiness. The antidepressant is quite strong, it is released strictly by prescription. But at the same time, the number of side effects for a drug of this type is small, dependence does not occur. Inconvenient doctors consider only a dosage of 150 mg. To achieve a stable therapeutic effect, many people need only 50 mg - the tablet has to be divided into three parts.
7 Afobazole
Country: Russia
Average price: 425 rub.
Rating (2022): 4.7
Afobazole is one of the best "light" antidepressants that have a calming effect on the nervous system. Thanks to this, it can be bought at almost any pharmacy without a prescription from a specialist. Domestic production allows not to overestimate the price of the drug. It is produced in two dosages, 5 and 10 mg each, with a varied number of tablets per package: from 10 to 120 pieces. You can set the daily rate yourself by following the instructions. To achieve the maximum effect, it is best to drink tablets in courses lasting from two weeks.
Due to the "lightness" of the drug and a competent set of components, side effects occur in isolated cases, which is a huge advantage over analogues. Numerous positive reviews, instant effect and attractive price make the product popular among Russian home first aid kits. It eliminates the feeling of increased anxiety, irritability and tension. This is a great product for those who lead a multi-functional lifestyle and want to be able to do everything without taking a big toll on their mental health.
6 Escitalopram
Country: Belarus
Average price: 270 rub.
Rating (2022): 4.8
One of the most popular new generation remedies against mental disorders, which has incredible effectiveness, noted by many experts and confirmed by numerous responses. White round convex tablets have helped more than one generation to return the nervous system to the right track. Doctors recommend them for depressive episodes, panic attacks and nervous disorders. A prescription drug is released, because it belongs to the group of potent drugs.
Contraindications to the use of the drug are minimal, which is a great advantage over others. The manufacturer recommends using it only for adults, only in rare cases it is prescribed for teenagers. Side effects are rare among patients, and they are not so terrible: dizziness, nausea, loss of appetite, urinary retention, headache, etc. The daily rate is 1-2 tablets, and the course can last from 1 to 2 months. Cancellation of the drug, like most of this group, must be done in stages.
5 Zoloft
Country: Italy - USA
Average price: 478 rub.
Rating (2022): 4.8
Foreign analogue of the well-known Russian "Thorin" with the active ingredient sertraline. A drug with proven effectiveness and a good reputation. It differs from the domestic one in that more expensive and purer raw materials are used in production. Also, fewer excipients are used. Their appearance is also different, which allows you to quickly distinguish a fake from the original. Foreign tablets have an oblong shape and the manufacturer's logo.
The tool does not cause dependence and weight gain with long-term use - these are its main advantages. Often, experts recommend it for panic attacks, social phobias, as a preventive measure to avoid depression. The effective remedy has several side effects that were noted in the reviews: drowsiness is felt, aggressiveness increases, appetite decreases and dry mouth appears. It should be taken once a day, starting with a small dose and not focusing on meals, gradually increasing the dosage. The medicine can be used by anyone over the age of six.You can buy it in almost any pharmacy.
4 Mirtazapine
Country: Russia
Average price: 734 rub.
Rating (2022): 4.8
Tetracyclic antidepressant with a pronounced anxiolytic and sedative effect. Recommended for the appointment of depression with sleep disorders, weight loss, suicidal thoughts. In therapeutic doses, it has a fairly good tolerance, side effects usually appear only at the beginning of treatment. Due to the decrease in concentration, care must be taken when driving.
Most often, doctors prescribe purple pills of a new generation from a domestic manufacturer to those who cease to enjoy life, experience a sense of joy, who lose interest in the events around him, feel physical inhibition, quickly lose weight and have a good healthy sleep. Tablets can only be purchased by prescription and only by persons over 18 years of age. The price of the “opponent of depression” is perhaps the most democratic, given its excellent performance. This is the best medicine in terms of price-quality ratio.
3 Fevarin
Country: France, Netherlands
Average price: 840 rub.
Rating (2022): 4.9
Fluvoxamine as an active ingredient is found in several types of medicinal products, but here we are talking about the drug of the same name of the Dutch-French origin Fevarin. His performance was marked by experts for a solid "four". This applies to both effect and portability.The rating was reduced only for side effects, which include a decrease in libido, the occurrence of headaches, and one of the rarest - a high probability of infection in the respiratory system.
Doctors recommend using it for depression of various degrees of severity, for obsessive-compulsive disorders and panic attacks. As you can see, the scope is small, which affects the availability of the drug: there are problems with the purchase of tablets due to their low prevalence, in contrast to broad-spectrum products. Before use, it is necessary to consult a specialist for a competent calculation of the daily dosage and duration of the drug.
2 Paxil
Country: Poland
Average price: 380 rub.
Rating (2022): 4.9
A large number of doctors prescribe this particular drug when the first signs of nervous disorders are detected. The main disadvantage is that it is sold strictly according to the doctor's prescription. Due to the wrong dosage, you can face a lot of unpleasant consequences, so the recovery course should be taken with great attention. The active substance - paroxetine in a short time will help to join the normal rhythm of life, get rid of insomnia, relieve stress and anxiety.
The results are noticeable after a few days of use, but you should not leave it immediately after a positive trend is noticed. As for the intake, it is best to drink tablets in the morning after breakfast, they should not be crushed, chewed, broken, you just need to swallow. With the manifestation of strange symptoms and poor health, the reception should be interrupted slowly, gradually reducing the daily dose.A new generation antidepressant should not be used by persons under 18 years of age, pregnant women and allergy sufferers. This is one of the effective medicines, provided that all recommendations are followed.
1 Ixel
Country: France
Average price: 1700 rub.
Rating (2022): 5.0
An effective new generation antidepressant that is a selective monoamine reuptake inhibitor. Absolutely no sedative effect, no negative impact on cognitive functions. Stimulating, activating effect allows it to be used for prolonged episodes of depression, occurring with melancholy and apathy. It is often prescribed by doctors for complex, severe conditions, when tricyclic drugs have not been effective enough.
There are side effects, but in a smaller amount compared to older generation drugs. Due to the pronounced stimulating effect, especially at the beginning of treatment, the drug can cause increased anxiety, so it is usually prescribed in combination with tranquilizers. The antidepressant is available in two dosages to treat depression of varying severity. One of the few drawbacks of the drug is its high cost.