№ |
Name |
Rating |
Nomination |
1 | Controloc | 4.61 | The original drug based on pantoprazole |
2 | Omez | 4.57 | The best ratio of price and quality |
3 | Emanera | 4.55 | Inexpensive Fifth Generation PPI |
4 | Nexium | 4.51 | State of the art IPP |
5 | Omeprazole | 4.49 | The most popular. Best price |
6 | Razo | 4.47 | Inexpensive generic based on rabeprazole |
7 | Pariet | 4.45 | The original fourth-generation PPI |
8 | Ortanol | 4.41 | Can be bought without a prescription |
9 | Lancid | 4.32 | High bioavailability |
10 | Nolpaza | 4.21 |
Proton pump inhibitors are designed to reduce the production of hydrochloric acid. The blocker works at the level of the parietal cell membrane, which is much safer and more effective than the use of antisecretory drugs. The first PPI, which was omeprazole, was created in 1979, and now this group of drugs has five generations, all of which remain popular and in demand.
Preparations from the PPI category differ in different bioavailability. Due to its frequent use, omeprazole-based agents are found to be resistant in some cases.All proton pump blockers are prescription drugs, but before buying them, you need to visit a doctor not only to get a prescription, but also to choose the best and most effective one, depending on the disease and the characteristics of its course of the drug.
Our ranking of proton pump inhibitors is based on the popularity of the drugs. To determine it, reviews about them left by users on the sites Yandex.Market, Otzovik, Otabletkah, Protabletky, IRecommend, Vrachi.rf were analyzed. Also, when compiling the TOP, the cost of funds, their composition and safety were taken into account.
Top 10. Nolpaza
- Average price: 340 rubles. (28 tab. 20 mg)
- Active ingredient: pantoprazole
- Manufacturer: KRKA (Slovenia)
Nolpaza is a proton pump blocker based on pantoprazole. This active ingredient belongs to the first generation of PPIs, but is considered to be sufficiently effective even now. The drug is prescribed both for the treatment of gastrointestinal diseases associated with acidity, and for prophylactic purposes when taking certain drugs that adversely affect the state of the stomach. The cost of the medicine is in the middle price range, two dosages and packages with different numbers of tablets are offered. Nolpaza's reviews are different, not everyone is fully satisfied with this drug, but there are those who are satisfied with it. Some write about the need for a double dose. Others note that they noticed improvements only after 5-6 days of use.
- PPI based on pantoprazole
- average price
- Multiple dosages
- Packs of various sizes
- There are negative reviews
Top 9. Lancid
Lancid, like other PPIs based on lansoprazole, is highly bioavailable, works faster and more efficiently than analogues.
- Average price: 320 rubles. (30 tab. 15 mg)
- Active ingredient: lansoprazole
- Manufacturer: Micro Labs Limited (India)
Lancid is one of the few representatives of proton pump blockers containing lansoprazole as an active ingredient. The drug is less common than analogues based on omeprazole and pantoprazole, but deserves to be included in the list of the best. Lansoprazole is one of the most bioavailable PPIs, which makes it quicker to act and relieve symptoms in the shortest time. In most cases, a single dose in the morning is sufficient. There are very few reviews about this remedy, it is prescribed infrequently, but most doctors speak extremely positively about it.
- Lansoprazole-based drug
- High bioavailability
- Quick result
- Few reviews
Top 8. Ortanol
The drug Ortanol at a dosage of 10 mg can be purchased at pharmacies without a prescription, which distinguishes it from analogues.
- Average price: 130 rubles. (28 tab. 20 mg)
- Active ingredient: omeprazole
- Manufacturer: Lek d.d. (Slovenia)
Ortanol is one of the proton pump inhibitors based on omeprazole. The Slovenian-made drug optimally combines cost and quality, although it is not the most popular in its category. Its reception allows you to quickly lower the acidity of the stomach, relieve heartburn and relieve unpleasant symptoms. The drug in a dosage of 10 mg can be bought at pharmacies without a prescription, the release forms of 20 and 40 mg are prescription.It is the minimum dosage that is most popular and is used by many to eliminate heartburn without consulting a doctor. Despite the availability of cheaper analogues, Ortanol still finds its consumer.
- Renowned manufacturer
- There is an over-the-counter dosage
- Acceptable cost
- More expensive than a number of analogues
Top 7. Pariet
Pariet is an original drug based on rabeprazole, which is a fourth, penultimate generation proton pump inhibitor.
- Average price: 1350 rubles. (14 tablets of 10 mg)
- Active ingredient: rabeprazole
- Manufacturer: Bushu Pharmaceuticals (Japan)
Pariet is an original drug based on rabeprazole, which belongs to the fourth generation of PPIs. The drug costs well above average, but many doctors call it the best and recommend it to their patients for the treatment of ulcers and erosions of the stomach or esophagus, gastritis and other gastrointestinal problems associated with high acidity. Despite the high price, there are not so few reviews about the drug, and it gets high ratings in them. Many note an improvement in well-being literally after the first application, a quick positive result of treatment, which is not achieved against the background of taking other blockers. A big advantage is the availability of release forms of 10 and 20 mg, as well as 14 and 28 tab.
- Original drug
- fourth generation PPI
- Two forms of release
- Small tablet size
- Very high cost
Top 6. Razo
Razo cannot be called a cheap drug, but against the background of others, also produced on the basis of rabeprazole, it is relatively inexpensive.
- Average price: 460 rubles. (30 tab. 20 mg)
- Active ingredient: rabeprazole
- Manufacturer: Dr. Reddy's (India)
Proton pump blocker Razo from Indian manufacturer Dr. Reddy's can not be attributed to the number of popular drugs, but there is no doubt about its quality. The medicine costs more than other PPIs, while it is a generic, and not the original, although it is of high quality. When compared with the original medicine, the cost is not so high. The rabeprazole-based agent begins to act within an hour and retains its activity for at least a day, so it is enough to take it once a day. The maximum result is observed on the third day of application. The people who took this drug as its main disadvantage name the cost. Everyone responds positively to its effectiveness, separately noting the absence of side effects and the convenience of taking it regardless of food.
- Quality generic
- Renowned manufacturer
- Fast action
- Fourth generation API
- High price
Top 5. Omeprazole
Omeprazole is the most popular of the PPIs in the ranking, for which we were able to find the largest number of reviews.
Omeprazole is the most affordable proton pump inhibitor and the winner in the "Best Price" category.
- Average price: 33 rubles. (30 tab. 20 mg)
- Active ingredient: omeprazole
- Manufacturer: ProMed (Russia)
Omeprazole is an inexpensive but effective PPI produced by several domestic manufacturers. The medicine is well known to doctors and patients, is in demand and trust. It is prescribed to reduce the acidity of the stomach, as well as to prevent side effects while taking non-steroidal anti-inflammatory drugs and chondroprotectors.Side effects on Omeprazole are possible, but in practice they are rare. The low price and long-term fame made the drug incredibly popular. Although it is a prescription drug, it is sold freely in many pharmacies.
- Cheap
- Known for many years
- Lots of positive feedback
- First generation API
Top 4. Nexium
Nexium is an original drug based on esomeprazole, which is a proton pump blocker of the latest generation.
- Average price: 240 rubles. (28 tab. 20 mg)
- Active ingredient: esomeprazole
- Manufacturer: AstraZeneca (Sweden)
Nexium is an original proton pump inhibitor based on esomeprazole. It belongs to the fifth generation of IPP and is considered one of the most modern and effective. Many doctors call it the best and prescribe it if the analogues are not effective enough. It costs a little more than other blockers, but the price is still relatively low. With gastritis, ulcers and esophagitis, Nexium copes well with the symptoms and has a healing effect. It is enough to take 1 time per day, there are dosages of 20 and 40 mg. Side effects are practically not mentioned in the reviews. Most of those who have tried this drug in the future choose only it.
- Original drug
- Fifth generation API
- Modern and efficient
- Slightly more expensive than analogues
See also:
Top 3. Emanera
Emanera is a relatively inexpensive drug that belongs to the fifth generation PPI and is one of the most modern and effective.
- Average price: 230 rubles. (28 tab. 20 mg)
- Active ingredient: esomeprazole
- Manufacturer: KRKA (Slovenia)
Emanera is a generic drug based on esomeprazole, which is not inferior to the original in terms of cost and quality. It belongs to the fifth generation proton pump inhibitors, that is, it is one of the most modern and effective. For any problems of the gastrointestinal tract associated with high acidity, taking this medication allows you to achieve rapid relief from the condition. Most often it is prescribed as part of complex therapy for ulcers and gastritis. The drug is available in dosages of 20 and 40 mg, a doctor's consultation will help you choose the optimal one. Both doctors and patients leave only positive feedback about Emaner, trusting the quality of this medicine.
- Fifth generation PPI
- Two dosages
- Adequate quality cost
- Generic
See also:
Top 2. Omez
Omez - is relatively inexpensive, enjoys considerable popularity and receives high marks in reviews, optimally combining price and quality.
- Average price: 170 rubles. (30 tab. 20 mg)
- Active ingredient: omeprazole
- Manufacturer: Dr. Reddy's (India)
Omez is one of the most commonly prescribed drugs from the group of proton pump inhibitors. The active substance omeprazole belongs to the first generation PPI, but continues to be in demand due to the optimal combination of cost and quality. The drug begins to act on average within an hour, and its maximum effect develops after 2 hours. This means that it is less suitable for the relief of acute symptoms, and more suitable for course administration.Omez is prescribed for both therapeutic and prophylactic purposes, for example, when taking non-steroidal anti-inflammatory drugs. There are a lot of reviews about the drug, it gets very high ratings in them, although many doctors tend to prescribe more modern, but also more expensive drugs.
- Average price range
- Renowned manufacturer
- Lots of positive feedback
- First generation drug
See also:
Top 1. Controloc
Controloc is an original German PPI based on the active ingredient pantoprazole. It is more expensive than analogues, but the quality is appropriate.
- Average price: 370 rubles. (14 tab. 20 mg)
- Active ingredient: pantoprazole
- Manufacturer: Takeda (Germany)
Controloc is an original drug based on pantoprazole, prescribed for ulcers, erosive lesions, as well as in complex therapy in the treatment of gastritis. It is available in dosages of 20 and 40 mg, the choice of the optimal one depends on the characteristics of the course of the disease and the patient's condition. Since the active ingredient in the composition has a low frequency of drug interactions, this drug is often prescribed to those who take a large list of other drugs. Side effects on the background of taking are extremely rare and this is another reason why this remedy is in demand and trust. The main disadvantage is the high cost, especially compared to generics with the same composition.
- Original drug
- Minimal drug interactions
- Two dosages
- Minimal risk of side effects
- High price
See also: