№ |
Name |
Rating |
Nomination |
1 | Hairabezol | 4.65 | Persistent relief of heartburn |
2 | Rabelok | 4.63 | The largest selection of dosage forms |
3 | Controloc | 4.55 | Best quality |
4 | Losek Maps | 4.49 | The original drug omeprazole |
5 | Razo | 4.48 | Ease of reception |
6 | Nexium | 4.42 | Original drug at the price of analogues |
7 | Emanera | 4.40 | Best price |
8 | Nolpaza | 4.32 | Optimal ratio of efficiency and price |
9 | Pariet | 4.25 | The fastest action |
10 | Sanpraz | 4.04 | Does not interact with other drugs |
Omeprazole is one of the most common drugs for the treatment of stomach diseases. It belongs to the proton pump inhibitors (PPIs), which inhibit the secretion of hydrochloric acid. In other words, the substance reduces the acidity of gastric juice, due to which it removes heartburn, alleviates the condition with gastritis and ulcers. This is one of the cheapest inhibitors, which, despite the low price, has many advantages. Omeprazole is suitable for long-term use, rarely gives side effects and in most cases helps to cope with the unpleasant symptoms of gastritis.But with peptic ulcer and other serious diseases, it may not show high enough efficiency. In these cases, doctors are considering new generation omeprazole analogues. Most of them are more expensive, but give better treatment results. PPIs are divided into two generations. The first generation is omeprazole and lansoprazole, the second generation is pantoprazole and rabeprazole. PPI stereoisomers are isolated separately. They belong to the latest generation of drugs. These are esomeprazole and dexlansoprazole.
Comparison of analogues of Omeprazole according to the main indicators
Name | average cost | Active substance | Producing country |
Omeprazole | 31 rub. | omeprazole | Russia |
The best analogues of Omeprazole of the new generation | |||
Losek Maps | 412 rub. | omeprazole | Sweden |
Pariet | 2278 rub. | rabeprazole | Japan |
Emanera | 209 rub. | esomeprazole | Slovenia |
Controloc | 626 rub. | pantoprazole | Germany |
Nolpaza | 372 rub. | pantoprazole | Russia |
Hairabezol | 557 rub. | rabeprazole | India |
Nexium | 447 rub. | esomeprazole | Sweden |
Rabelok | 380 rub. | rabeprazole | India |
Razo | 469 rub. | rabeprazole | India |
Sanpraz | 485 rub. | pantoprazole | India |
Top 10. Sanpraz
The active substance pantoprazole has a low degree of interaction with other drugs. Therefore, it is prescribed to patients who are forced to take a lot of pills.
- Average price: 485 rubles.
- Country: India
- Manufacturer: Sun Pharmaceutical Industries Ltd
- Active ingredient: pantoprazole
There are not so many proton pump inhibitors based on pantoprazole. "Sanpraz" is one of the most common analogues, often prescribed by gastroenterologists.It is preferred if the patient is simultaneously taking drugs for other diseases, since pantoprazole has a low drug interaction. This is especially true for blood-thinning drugs. At the same time, relief comes quickly even when taken once a day. Side effects are not common, but dry mouth and constipation are possible. The price for the course is slightly above average, but in terms of effectiveness, Sanpraz is still somewhat inferior to some other drugs based on pantoprazole. For this, gastroenterologists slightly reduce the assessment of the drug, considering it worthy, but not the best among analogues.
- Often prescribed by gastroenterologists
- Low interaction with other drugs
- Convenient tablet form
- Effect already at the beginning of the course
- Possible side effects
- Not the most effective of pantoprazoles
Top 9. Pariet
Pariet relieves stomach pain with peptic ulcer after taking the first pill. It is the fastest acting proton pump inhibitor.
- Average price: 2278 rubles.
- Country: Japan
- Manufacturer: Bushu Pharmaceuticals
- Active ingredient: rabeprazole
One of the most effective new generation PPIs. As a substitute for Omeprazole, the drug should be considered if the prescribed treatment does not give the desired therapeutic effect. The original drug rabeprazole brings relief from gastric ulcer already on the first day of admission, so doctors prescribe it in the acute phase. Against the background of treatment, they note a very fast positive dynamics, which is not typical for other analogues in the pharmacological group.This is a modern drug without side effects, which can be called one of the best remedies for peptic ulcer, gastric erosion. The only serious drawback is the very high price, especially for the course. Many patients cannot afford it, because of this, doctors rarely prescribe Pariet, preferring cheaper analogues.
- Improves the condition on the first day of admission
- Fast positive dynamics
- High quality original product
- Rave reviews from doctors
- Very high price
Top 8. Nolpaza
A relatively cheap analogue of pantoprazole is not inferior in effectiveness to expensive drugs. A pronounced effect is noticeable after 3-5 days of admission.
- Average price: 372 rubles.
- Country Russia
- Manufacturer: KRKA-RUS
- Active ingredient: pantoprazole
Doctors consider Nolpaza one of the best proton pump inhibitors. Compared to other drugs based on pantoprazole, the drug is inexpensive, but shows no less effectiveness. Available in the form of small tablets, easy to swallow. The main active ingredient does not interact with other drugs, so doctors prefer the drug when choosing therapy for patients with concomitant diseases. Portability is good, without side effects. A slight improvement is observed after the first dose, a pronounced result after 3-5 days. Availability can also be attributed to the pluses - the drug is always in pharmacies. Cons - it is contraindicated for pregnant women, it is prescribed for relatively short courses, uncontrolled intake is unacceptable.
- Does not interact with other drugs
- Gives no side effects
- Pronounced action after 3-5 days
- Comes in the form of small tablets
- Contraindicated in pregnant women
- Use only as directed by a physician
Top 7. Emanera
Of the substitutes for Omeprazole, this drug has the most affordable price. A new generation medicine costs a little more than 200 rubles.
- Average price: 209 rubles.
- Country: Slovenia
- Manufacturer: KRKA
- Active ingredient: esomeprazole
The modern replacement for omeprazole of the new generation is also a proton pump inhibitor, but has a higher bioavailability. Therefore, the effect of treatment is achieved much faster. "Emanera" already at the beginning of the course stops the symptoms of stomach diseases. Taking courses reliably protects against relapses. Among all drugs based on esomerpazole, many doctors prefer the variant of the pharmacological company Krka. "Emanera" is an order of magnitude more effective than cheap "Omeprazole", but at the same time it also differs in more than an affordable price. This is the best option for those who are looking for a modern replacement for an outdated product without breaking the bank. The drug is practically without side effects, but requires gradual withdrawal in order to avoid relapses.
- Brings relief quickly
- Optimum price-performance ratio
- Gives no side effects
- New generation drug
- Requires phasing out
- Not sold in all pharmacies
Top 6. Nexium
Nexium is the cheapest original drug among proton pump inhibitors. It is high quality and efficient.
- Average price: 447 rubles.
- Country: Sweden
- Manufacturer: AstraZeneca AB
- Active ingredient: esomeprazole
The original drug esomeprazole of the famous brand Astra Zeneca. A few years ago it was very expensive, was not available to many patients. Then the price dropped several times due to the availability policy of the pharmaceutical company. The drug is well researched, safe and effective in the treatment of diseases of the stomach, esophagus and 12-colon. The PPI stereoisomer is more bioavailable, so a pronounced therapeutic effect is achieved already in the first days of treatment. The drug is prescribed for long courses, well tolerated by patients. Like all such drugs, it can cause a "rebound syndrome" when canceled, which is manifested by severe heartburn and deterioration of well-being. To avoid this, doctors prescribe a gradual withdrawal regimen.
- Original drug at an affordable price
- Good research base
- Positive feedback from patients and doctors
- Fast action and efficiency
- If canceled incorrectly, gives "rebound syndrome"
Top 5. Razo
Razo comes in the form of small tablets that are easy to swallow. And you only need to take them once a day.
- Average price: 469 rubles.
- Country: India
- Manufacturer: Dr. Reddy's
- Active ingredient: rabeprazole
High-quality rabeprazole drug from a reliable Indian company. It quickly copes with high acidity, eliminates heartburn, and with long-term course intake, heals erosions and ulcers. It is often used in complex therapy. Gastroenterologists prescribe "Razo" for long courses until a stable therapeutic effect is achieved. Conveniently, the absorption of the active substance does not depend on food intake. You need to take the drug once a day, at any time of the day.The drug is produced in the form of small tablets of 10 mg and 20 mg, the package is designed for a month of admission. With this in mind, the price of the course is quite affordable. Of the side effects, patients in the reviews occasionally call nausea at the beginning of the course. The disadvantages include the availability of not all pharmacies.
- High efficiency at an affordable price
- Easy-to-swallow small tablets
- Take once a day
- Quickly relieves heartburn and stomach pain
- Not sold in all pharmacies
- Nausea at the beginning of the course
Top 4. Losek Maps
Losek Maps belongs to the first generation of PPIs, but in terms of quality and effectiveness it is many times superior to the Russian Omeprazole. This is the original drug, often prescribed by doctors.
- Average price: 412 rubles.
- Country: Sweden
- Manufacturer: AstraZeneca AB
- Active ingredient: omeprazole
The original "brand" drug omeprazole, despite the emergence of new generation tablets, still remains the gold standard of antisecretory therapy. He owes this to safety and proven effectiveness. The Russian "Omeprazole" is a generic and is significantly inferior to the original drug in terms of therapeutic effect. This is noted by both doctors and patients. Losek MAPs is the best drug based on omeprazole. Steady improvement is observed after a short course of use. With long-term therapy, the frequency of relapses is reduced. The high quality of the drug minimizes the severity of side effects. And safety allows you to prescribe it to pregnant women to relieve heartburn.Doctors call the only significant drawback the high cost of the drug, due to which many patients refuse the original drug in favor of a cheap Russian generic.
- High quality original product
- Rapid therapeutic effect
- No Side Effects
- Positive feedback from doctors
- High price
Top 3. Controloc
A high-quality drug made in Germany has earned the trust of gastroenterologists and patients. It quickly helps to cope with stomach diseases without side effects.
- Average price: 626 rubles.
- Country: Germany
- Manufacturer: Takeda
- Active ingredient: pantoprazole
A high-quality drug for the treatment of gastritis, peptic ulcer and other diseases of the stomach. It belongs to a new generation of PPIs, well tolerated without side effects, provided that the dosage is correctly prescribed and gradual withdrawal. It comes in the form of tablets, which many patients like because they are easier to swallow than capsules. The drug is made in Germany, it is not cheap, but the effectiveness is high. This is a worthy substitute for Omeprazole - a more modern and effective drug. A feature of pantoprazole is the minimum frequency of drug-drug interactions, which makes it possible to prescribe "Controloc" to patients who simultaneously take many drugs. Based on the use of the drug in practice, doctors leave only positive reviews. Patients are satisfied with the result, but the price seems high to them.
- No Side Effects
- Does not interact with other drugs
- Convenient tablet form
- High quality and efficiency
- Expensive drug
See also:
Top 2. Rabelok
The drug is available in tablets of various dosages and as a solution for injection. This gives the doctor more opportunities to select an individual treatment regimen and quickly help patients.
- Average price: 380 rubles.
- Country: India
- Manufacturer: Cadila Healthcare
- Active ingredient: rabeprazole
An effective new generation drug, one of the most successful substitutes for Omeprazole. It is widely used in gastroenterology, is prescribed for gastritis, ulcers, esophagitis and other diseases of the stomach. Available in tablets of 10 mg and 20 mg, which allows you to more accurately select an individual dosage. There is a form of solution for injection for quick relief in severe cases. It acts quickly, gives a stable therapeutic effect, subject to the treatment regimen. There are no undesirable side effects; when canceled, it does not cause a pronounced “rebound syndrome”. It can be prescribed for long courses. According to the reviews of doctors and patients, erosion completely heals already in 8 weeks of taking it, the effect of the treatment persists for a long time. A small minus - the drug is not sold in all pharmacies.
- Different forms of release and dosage
- High efficiency
- No side effects and "rebound syndrome"
- Long-term effect after the course of administration
- Low availability in pharmacies
See also:
Top 1. Hairabezol
Hairabezol quickly eliminates heartburn and prevents its reappearance. The drug effectively reduces acidity, helps to cope with diseases of the stomach.
- Average price: 557 rubles.
- Country: India
- Manufacturer: HiGlance
- Active ingredient: rabeprazole
A high-quality and effective substitute for "Omeprazole", which is used for diseases of the esophagus, stomach, is often included in the complex therapy of Helicobacter pylori. Quickly and firmly stops heartburn, in combination with other drugs gives 100% healing of erosions and ulcers. It is prescribed for long courses with further gradual withdrawal in order to avoid relapses. Available in the form of small tablets, easy to take. The drug is not the cheapest, but the price matches the quality. Side effects when taken are rare, in some cases, mild nausea is possible in the first two weeks. But many doctors and patients consider Hairabezol one of the best substitutes for omeprazole. The drug is safe, but contraindicated in children under 18 years of age, pregnant and lactating women.
- Firmly relieves heartburn
- High efficiency in erosion and ulceration
- Easy-to-take small tablets
- Rapid therapeutic effect
- May cause nausea at the start of use
- Contraindicated in children and pregnant women
See also: